证候要素在阿尔茨海默病证候分型中的作用

摘要

This study was aimed to use epidemiological survey method for identifying Alzheimer's disease ( AD ) syndrome elements in order to determine their syndromes type. The epidemic survey was done in three districts of Taiyuan city to set database. Data of effective cases were collected for both modern medicine information and tra-ditional Chinese medicine (TCM) information through four diagnostic methods. The data were analyzed to extract syndrome elements objectively. The results showed that there were 13 syndrome elements of AD extracted from this study, which include qi deficiency, yang deficiency, blood deficiency, yin deficiency, blood stasis, phlegm-turbid, qi constraint, internal dampness, qi stagnation, toxin, internal wind, internal fire, yang hyperactivity. There were four elements of disease location , namely , the kidney , spleen , heart , liver . There were 41 different kinds of names after the combination of syndromes and locations, which covered 80% of AD. It was concluded that the es-tablishment of AD syndrome elements and the combination is the feasible way to standardize the syndrome classi-fication standardization .%目的：运用流行学调查方法提取阿尔茨海默病的证候要素，确定该病证候分型。方法：对太原市3个地区进行流行学调查，将有效病例进行西医疾病的信息采集和中医证候四诊信息的采集，建立数据库，进行统计学处理，客观化提取并确定证候要素。结果：提取出阿尔茨海默病的证候要素13个，即气虚、阳虚、血虚、阴虚、血瘀、痰浊、气郁、内湿、气滞、毒邪、内风、内火、阳亢；病位要素4个，即肾、脾、心、肝；经过“应证组合”证候类型41种，涵盖率达80%。结论：阿尔茨海默病证候要素的确立和应证组合是确立证候分型规范化研究的可行途径。