Objective To explore the possible pathophysiology of functional constipation with colonic transit test, anorectal manometry, rectal pressure-stimulation, and to assess its variety of manometric abnormalities and visceral perception. Methods According to diagnostic criteria of Roman III, the data of S3 patients (both in out-patient and in-patient department) was collected. Total and segmental colonic transit times and transit indexes were assessed radiographically by radiopaque markers method, adopting; standard anorectal manometry was ad-opted to monitor the anorectal function, and rectal visceral perception thresholds were examined after rectal pres-sure-stimulation. Results The research results demonstrated that the colonic transit time in functional consti-pation patients was significantly prolonged, major in the area of right colon and anorectum. Patients also had the abnormalities in anorectal motility. Conclusion Abnormal colonic transition, abnormal anorectal motility and abnormal visceral perception are often found in patients with functions constipation.%目的 探讨功能性便秘可能的病理生理学机制. 方法采用不透X线标志物测定53例功毹性便秘忠者全结肠和结肠节段通过时间,通过直肠球囊内注入空气,研究直肠容量刺激对初始感觉阈值、最大耐受性的影响. 结果功能性便秘患者结肠通过时间延长,且结肠通过时间延长主要发生在左半结肠区、乙状结肠直肠区,并存在肛门直肠动力异常. 结论结肠直肠肛门动力紊乱与直肠感觉异常均参与功能性便秘的发展.
展开▼
