Objective To observe the effect of azithromycin sequential therapy combined with in-halated budesonide in treating mycoplasma pneumonia children.Methods Selected 76 gestational diabetes mycoplasma pneumonia children in our hospital from June 2012 to May 2014,they were randomly divided into experimental group and control group.The corresponding random numbers of the experimental group were even,and the corresponding random numbers of the control group were odd,and there were 38 patients in each group.The cases of control group were given azithromycin sequential therapy ,and at the same time,the cases of experimental group were treat-ed with azithromycin sequential therapy combined with inhalated budesonide.Then compared the effect of treatment, the clinical symptoms and signs and adverse reaction of the two groups.Re-sults The total effective rate in experimental group was 97.37%,higher than that of the control group-92.11%,but the difference was not statistically significant(χ2=1.06,c>0.05). The time of cough disappeared,fever subsided,pulmonary rales disappeared and length of stay in experimental group was significantly shorter than that of the control group(P<0.01).The rate of adverse reaction in the experimental group and the control group were 10.53% and 13.16%, and the difference was not statistically significant(χ2=0.13,P>0.05).Conclusions Azithromycin sequential therapy combined with inhalated budesonide in treating mycoplasma pneumonia children can significantly improve the pa-tients’ clinical symptoms and signs, shorten the treatment time, it was worthy of clinical promo-tion.%目的：观察阿奇霉素序贯疗法联合布地奈德雾化吸入法治疗小儿支原体肺炎的临床疗效。方法选取2012年6月～2014年5月我院诊治的小儿支原体肺炎患者76例，按照随机数字表法分为试验组和对照组，各38例。对照组患儿采用阿奇霉素序贯疗法治疗，试验组在对照组的基础上采用布地奈德雾化吸入法治疗，观察并比较两组的治疗效果、临床症状和体征的变化以及不良反应发生情况。结果试验组的治疗总有效率为97.37%，高于对照组（92.11%），但不具有统计学意义（χ2=1.06，P＞0.05）；两组咳嗽消失时间、发热消退时间、肺部啰音消失时间以及住院时间比较，试验组所需要的时间均明显短于对照组，差异具有统计学意义（P＜0.01）；试验组和对照组的不良反应发生率分别为10.53%和13.16%，且两组的差异不具有统计学意义（χ2=0.13，P＞0.05）。结论阿奇霉素序贯疗法和布地奈德雾化吸入法治疗小儿支原体肺炎能够明显改善患儿的临床症状和体征，缩短治疗时间，值得临床推广。
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