吡唑醚菌酯原药的主要杂质及合成研究

摘要

There were three impurities with relatively high contents in pyraclostrobin TC during the synthesis process. The impurities were prepared from pyraclostrobin TC and their structures were characterized by NMR and MS. The standard material of pyraclostrobin was also prepared through recrystallization. The study provided support for the synthesis process of pyraclostrobin TC and full components analysis.%吡唑醚菌酯原药中含有3个在生产过程产生的含量较高的杂质,以吡唑醚菌酯原药为原料,合成了这些杂质,NMR和MS表征了其结构,并通过对原药重结晶纯化制得标准品,为吡唑醚菌酯原药合成工艺的控制和全组分分析提供支持.