卵巢癌二次探查手术前PET-CT检查的作用及临床意义

摘要

Objective To investigate the role of performance of integrated positron emission tomography and computed tomography (PET-CT) before second look operation (SLO) on patients with ovarian cancer.Methods The clinical data of 37 patients with ovarian cancer reached the admitted standard from February 2006 to December 2010 in our hospital were analyzed retrospectively,in which 16 patients were performed PET-CT.Results There were 67％ patients with ovarian cancer in pathological diagnosis in SLO group (control group),and 75 ％ in PET-CT performance group (T group).Compared with control group,less time was demanded during operation in the group of operation instructed by the results of PET-CT (S group)(P ＜ 0.01).Median survival time of S group was longer than that of control group.But there was no significant difference between control group and T group(P ＞0.05).Conclusion Performance of PET-CT before SLO on ovarian cancer could reduce operation time and prolong the survival time of patients with ovarian cancer.But the prognosis of operation instructed only by the results of PET-CT was not prior to SLO.%目的 探讨卵巢癌二次探查前行PET-CT检查的作用及临床意义.方法 回顾性分析2006年2月-2010年12月手术治疗的、符合纳入标准的37例卵巢癌(16例行PET-CT检查)病历随访资料,比较二次探查术与PET-CT检查用于指导患者手术治疗随访结果.结果 二次探查手术阳性率为67％；PET-CT检查阳性率为75％.PET-CT检查指导手术治疗组(S组)手术时间缩短,与直接二次探查手术组(对照组)相比,差异有统计学意义(P＜0.01)；S组中位生存时间较对照组延长(P＜0.05)；PET-CT检查组(T组即PET-CT检查后的手术及非手术病例)中位生存时间与行传统检查后直接行二次探查手术组相比,差异无统计学意义(P＞0.05).结论 PET-CT在二次探查手术前进行检查,可准确定位复发或转移部位,可缩短手术时间,延长术后患者生存期.但单纯以PET-CT结果为依据,判定患者是否需要二次手术,效果并不优于传统检查后行二次探查手术.