Objective: To know about the children hepatitis symptoms and changes after receiving vaccine and to provide scientific proofs for future hepatitis prevention. Methods: Analyzed the epidemic situation of hepatitis patients under 15 years old from 1982 to 2008. Results: There-were 546 hepatitis cases under 15 reported from 1982-2008, the annual average mobility rate was 14.40/100000. The highest mobility rate was in 1993 and the lowest in 2007; mobility rate of male was 3.24/100000, that of female was 1.72/100000(P < 0.01); 0-4 years old 8.15/100000,5-9 years old 18.16/100000,10-14 years old 16.68/100000(P < 0.01 ).There is a negative correlation between mobility rate and vaccine received rate under 15 years old(r=-0.78,P < 0.01). Conclusion: The mobility rate among children under 15 years old declined greatly. There is a negative correlation between mobility rate and vaccine received rate.%目的:了解接种乙肝疫苗后儿童乙肝发病特征及其变化,为乙肝防治提供科学依据.方法:对1982-2008年普兰店市15岁以下儿童乙肝疫情资料进行分析.结果:1982-2008年合计报告15岁以下乙肝病人546例,年均发病率为14.40/10万.其中,1993年最高(30.56/10万),2007年最低(0.00/10万)；男性(3.24/ 10万),高于女性(1.72/10万)(P＜0.01);0-4岁为8.15/10万,5-9岁为18.16/10万,10-14岁为16.68/10万(P＜0.01).15岁以下儿童乙肝年发病率与该人群乙肝疫苗年接种率呈高度负相关(r=-0.78,P＜ 0.01).结论:15岁以下儿童乙肝发病率有明显下降趋势,乙肝发病率与乙肝疫苗接种率呈高度负相关.
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