细胞响应纳米结构表面特性的行为和机制

摘要

It has become clear that cell behavior is affected by nanotopography. With the application of nanotechnology( nanoscale patterning and detection ) in nano-biomedicine, cells-nanostructure research were developing rapidly. Here is to trace the related studies, exploring cell behavior response to nanostructure, and the inductive potential mechanism of cell-nanostructure. Nanostructure surface characteristics include physical property and chemical property,here we are to discuss the geometry structure of nano materials influence on cell behaviors, including adherency, proliferation, and differentiation etc. .%纳米结构的表面特性与细胞行为密切相关.近20年来,纳米尺寸表面构建和检测技术的飞速发展,提供了多种精确构建纳米材料和观测的方法,这些技术在生物医药方面的广泛应用,促使"细胞-纳米结构"的研究迅速发展.在此探讨纳米结构表面特性对细胞行为的影响,归纳"细胞-纳米结构"中可能发挥作用的机制;纳米材料表面几何学结构对于细胞行为的影响,细胞行为包括黏附、增殖、分化等.