感觉神经末梢形态学研究方法及其在躯干和四肢软组织中的研究进展

摘要

感觉神经末梢(SNE)在躯干和四肢软组织疼痛、压痛、感觉异常等神经功能障碍中的作用,备受临床和基础研究者的重视,其手段部分程度上依赖于神经形态学的研究方法.神经形态学的研究始于中枢神经系统,并得到了迅速发展,建立在中枢神经系统上的银染法、免疫组化法和神经顺行示踪法等同样适用于针对SNE的研究.目前,研究SNE形态学的观察方法、躯体某些部位或解剖层次SNE的研究情况未见系统总结.现通过对不同方法的介绍,探讨SNE形态学在躯干和四肢中的研究情况.%The importance of sensory nerve ending(SNE )in torso and limbs pain,tenderness and paresthesia has received much attention in basic and clinical researches. The morphology of SNE techniques was commonly used in the process. These techniques originated from the study of center nerve system and developed rapidly. Silver staining. immunohistochemistry and horseradish peroxidase tracing method , building on center nerve system,is suitable to the SNE study. At present, there are few introductions to the methods and advances of morphology of SNE in torso and limbs. Different methods and their development in the study of SNE were reviewed in torso and limbs.