目的 探讨卡维地洛联合参麦注射液治疗慢性充血性心力衰竭的临床效果.方法 选择我院慢性充血性心力衰竭患者90例,随机分为观察组和对照组.两组患者均给予控制诱发因素、限制食盐摄入、充分休息等一般治疗.同时给予强心药物、血管扩张药物、利尿剂等.对照组采用以上治疗.观察组在对照组用药基础上给予卡维地洛口服,开始剂量为每次12.5 mg,每日2次,服用3 d后剂量改为每次25 mg,每日2次.同时给予参麦注射液80 mL静脉滴注,连续应用2周.采用超声心动图对两组患者治疗前和治疗后进行检查.结果 观察组治疗后左心室射血分数、每搏量和每分心排血量显著高于对照组,差异有统计学意义(P＜0.05);观察组总有效率与对照组比较,差异有统计学意义(P＜0.05).结论 卡维地洛联合参麦注射液能够显著提高慢性充血性心力衰竭患者心功能,改善临床症状和体征,临床效果显著.%Objective To discuss the clinical effect of carvedilol combined with shenmai injection for the treatment of chronic congestive heart failure. Methods 90 cases with chronic congestive heart failure were randomly divided into observation group and control group. Both groups were given general treatment such as inducing factors controlling, salt intake restriction and good rest. They were given cardiac strengthening drug, hemangiectasis drug and diuretic at the same time. Observation group was orally given carvedilol on the basis of control group , 12. 5 mg every time at first, twice daily, and then 25 mg every time after 3 days, twice daily. They were also given 80 mL of shenmai injection for intravenous drip for consecutive 2 weeks. Echocardiography was used before and after treatment for the examination of patients. Results Left ventricular ejection fraction, stroke volume and heart discharge blood per minute in observation group were obviously higher that in control group after treatment, the difference had statistical significance( P < 0. 05 ). The difference of the total effective rate in two groups had statistical significance( P <0. 05 ). Conclusion Carvedilol combined with shenmai injection can significantly improve patients' heart function and clinical symptoms, showing obvious efficacy.
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