Coronary heart disease is a chronic inflammatory reaction of vessel wall, inflammatory reaction within the coronary artery participates in the whole process of atherosclerosis. Inflammatory response involvies a variety of inflammatory factors, currently known including serum inflammatory factors , such as : soluble intercellular adhesion molecule-1 , interleukin-6 ,C-reactive protein, tumor necrosis factor-a, matrix metalloprotein-ases, nuclear factor k.B, tissue factor, fihrinogen, homocysteine, lipoprotein( a ),etc. , the role of which in the development process of coronary heart disease has been widely recognized.%冠心病是血管壁一种慢性炎性反应过程,冠状动脉内的炎性反应参与了动脉粥样硬化的全过程.炎性反应涉及多种炎性反应因子,目前已知的血清炎性因子,如可溶性细胞间黏附分子1、白细胞介素6、C反应蛋白、肿瘤坏死因子α、基质金属蛋白酶、核因子κΒ、组织因子、纤维蛋白原、同型半胱氨酸、脂蛋白(a)等,其在冠心病发生、发展过程中的作用已得到广泛认可.
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