重症急性胰腺炎(SAP)是一种临床表现凶险,并发症多,病死率高的疾病,在SAP的急性反应期常发生毛细血管渗漏综合征(CLS).但是,由于全身毛细血管渗漏综合征发病机制、病理特点、临床表现相对比较复杂,病期之间的界限模糊,并发症较多,治疗矛盾多,在临床治疗上往往易忽视全身CLS.CLS的出现往往加速SAP病情恶化,针对CLS不同环节的防治可以提高SAP患者的生存率,改善SAP患者的预后.%Severe acute pancreatitis ( SAP ) is a kind of disease with serious clinical symptoms, a variety of complications and high mortality. Capillary leakage syndrome ( CLS ), usually occurrs during the acute reaction period of SAP. However since the pathogenesis, clinical manifestation, pathological features of CLS are complex, CLS has many complications,, and there are many therapeutic paradoxs in the treatment of CLS. So,the clinical treatment tends to ignore CLS. The occurrence of CLS is often involved in the aggravation of SAP. The prevention and treatment of CLS from different aspects can increase the survival rate of SAP and improve the prognosis.
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