微量肝素钠治疗小儿重症肺炎的临床疗效

摘要

Objective:To investigate the clinical effect of trace heparin sodium in the treatment of pediatric severe pneumonia.Method:80 hospitalized children with severe pneumonia were selected from December 2011 to May 2013 in our hospital and according to the order of admission they were randomly divided into the treatment group and the control group, 40 cases in each group.The two groups were treated with with the conventional treatment of severe pneumonia.On the basis of conventional method,the treatment group was treated with heparin sodium in the dose of 6 U/kg,and infused intravenously every six hours,for 5 days.The therapeutic effects of the two groups were observed and compared.Result:In the treatment group 24 cases were markedly improved,effective was 14 cases,the total effective rate was 95.0%,in the control group 16 cases were markedly improved,10 cases were effective,the total effective rate was 65.0%,the total effective rate in treatment group was significantly higher than the control group,the difference was statistically significant(P<0.05). Conclusion:Trace heparin sodium in the treatment of children with severe pneumonia has no side-effect on platelets and blood coagulation mechanisms.Therapeutic effect is remarkable,safe and reliable.This method was worthy of lots of grassroots hospital clinical promotion.%目的：探讨微量肝素钠治疗小儿重症肺炎的临床疗效。方法：选取2011年12月-2013年5月本科收治的80例住院重症肺炎患儿，按照入院顺序随机将其分为治疗组和对照组各40例。两组患儿均按重症肺炎常规治疗，治疗组在此基础上加用肝素钠每次6 U/kg，静脉推注每6小时1次，连用5 d，观察比较两组患儿的临床疗效。结果：治疗组显效24例，有效14例，总有效率为95.0%，对照组显效16例，有效10例，总有效率为65.0%，治疗组的总有效率明显高于对照组，差异有统计学意义（P<0.05）。结论：微量肝素钠治疗小儿重症肺炎，对血小板及凝血机制无影响，疗效显著，安全可靠，值得广大基层临床推广。