血清β-hCG、雌二醇和孕酮联合检测在异位妊娠早期诊断与保守治疗中的价值

摘要

Objective:To investigate β-serum human chorionic gonadotroPin (β-hCG) estradiol (E2) and Progesterone (P) the determination of the early diagnosis of ectopic pregnancy, ectopic pregnancy conservative treatment selection and therapeutic value.Method:150 cases of ectopic pregnancy were selected as the group A, 100 cases of normal intrauterine pregnancy were selected as the group B.Theβ-hCG, E2 and P were determined by chemiluminescence. According to β-hCG, E2, P content in the blood, given conservative medical treatment, determined β-hCG, E2, P ectopic pregnancy treatment options significance.Compared successful conservative treatment group decreased serum β-hCG and P levels were within the normal range to the time required.The different of pre-treatment serum β-hCG, E2 and P levels and treatment outcome relationship were analyzed.Result:The serum β-hCG ,E2 and P in the group A were lower than the group B, the differences were statistically significant (P<0.05).Conservative treatment decreased serum P drug levels to normal less than the time required β-hCG drops to normal time required, the lower the P, E2 level, the success rate more high.Conclusion:Serumβ-hCG, E2 and the level of P is helpful to early diagnosis of ectopic pregnancy; serum P determination is a dynamic detection effect of conservative treatment of ectopic a superior evaluation of serum β-hCG of pregnancy; according to the content of blood β-hCG, E2, P for the treatment of early ectopic pregnancy options provide quantitative indexes.%目的：探讨血清β-人绒毛膜促性腺激素（β-hCG）雌二醇（E2）和孕酮（P）测定对异位妊娠早期诊断，异位妊娠保守治疗方法选择及疗效的价值。方法：选择异位妊娠患者150例（A组），正常宫内早孕者100例（B组）。采用化学发光法测定并比较两组血清β-hCG、E2和P的含量；根据血中β-hCG、E2、P的含量，给予药物保守治疗，判断β-hCG、E2、P对异位妊娠治疗方案选择的意义；比较药物保守治疗成功患者血清β-hCG和P水平下降至正常范围内分别需要的时间；分析治疗前不同血清β-hCG、E2和P水平与治疗结局的关系。结果：A组血清β-hCG、E2和P水平均低于B组，差异均有统计学意义（P<0.05）；药物保守治疗成功患者的血清P水平下降至正常所需要时间少于β-hCG下降至正常值所需的时间，E2、P水平越低，成功率越高。结论：血清β-hCG、E2和P水平有助于异位妊娠早期诊断。动态测定血清P是一种优于血清β-hCG的评估异位妊娠保守治疗效果的检测。根据血中β-hCG、E2、P的含量为早期异位妊娠的治疗方案的选择提供量化指标。