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莪术油葡萄糖注射液致过敏性休克临床观察

     

摘要

Objective To explore the characteristics of adverse reactions Zedoary Turmeric Oil and Glucose Injection. Methods 2 patients (patients 1 8 years of age, 2 12 years), intravenous drip Zedoary Turmeric Oil and Glucose Injection 5min anaphylactic shock. In 1 patients with dif iculty in breathing, sweating, pale, flaring nostrils, lips cyanosis, irritable mood. Disable Zedoary Turmeric Oil and Glucose Injection, given an intravenous bolus injection of dexamethasone 10 mg, 25 mg intramuscular promethazine 10min after the remission of symptoms; 2 patients with dry mouth, palpitation, shortness of breath, sweat, complexion is cadaverous, skin itching and, the whole body is algid, trance. Give a symptomatic treatment. Results The adverse reaction of Zedoary Turmeric Oil and Glucose Injection multi occurred in 1--5min, mostly al ergic reactions, independent of dosage. Conclusion To prevent al ergic reaction, can significantly reduce adverse reaction Zedoary Turmeric Oil and Glucose Injection.%目的:探讨莪术油葡萄糖注射液的不良反应的特点。方法2例患者(例18岁,例212岁),静脉滴注莪术油葡萄糖注射液5min出现过敏性休克。例1患者呼吸困难,大汗淋漓,面色苍白,鼻翼煽动,口唇发绀,情绪烦躁。停用莪术油葡萄糖注射液,给予静脉推注地塞米松10mg,肌注异丙嗪25mg 10min后症状缓解;例2患者口干,心慌,气短,冷汗,面色苍白,皮肤瘙痒继而出现,全身发冷,神志恍惚。给予对症处理后好转。结果莪术油葡萄糖注射液的不良反应多在1~5min内发生,主要是过敏反应,与用药剂量无关。结论预防过敏反应,能够明显减少莪术油葡萄糖注射液的不良反应。

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