长期高压氧治疗对糖尿病性脑血管疾病患者血糖代谢的影响

摘要

目的：本研究通过对34例长期进行HBO治疗的有糖尿病性脑血管疾病患者的血糖代谢三项化验指标变化情况进行分析，旨在讨论长期 HBO治疗对糖尿病性脑血管疾病患者血糖代谢指标的影响。方法34例有2型糖尿病性脑血管疾病患者随机分为高压氧综合治疗组（HBO组）17例，单纯药物治疗组（对照组）17例。对照组用二甲双胍100 mg/3次/d；尼莫地平30 mg/3次/d，加用抗血小板、调脂、降压等基础药物；HBO组在药物治疗组基础上加用高压氧治疗法。2个月为1疗程，观察患者治疗后的血糖代谢3项检查指标，并设对照组进行比较。结果高压氧综合治疗组总有效率明显高于对照组(P<0.01)。 HBO治疗组1疗程后，治疗组的血糖代谢指标改善及症状改善明显优于对照组(P<0.05)。结论高压氧综合治疗糖尿病性脑血管疾病，可有效地改善血糖代谢水平及脑血流循环，改善血糖代谢作用优于单纯药物组，起效快、效果好、安全性高。%Objecfive To investigate the dif erence of hemodynamics changes between HBO treatment and general treatment of transient ischemic at acks (TIAs)measured by Tran cranial Doppler. Methods 54 patients with TIAs were randomly divided into HBO treatment group (n=42) and Nimotop-aspirin control group (n=42); To observe the hemodynamics changes before and after the treatment,and analyze the results. Results There Was a markedly dif erence between the two groups (P<0.01). The hemodynamics changes of HBO group were superior to control group(P<0.05),and symptoms disappeared earlier than control group. Conclusions HBO treatment is a fast, ef ective and safe method in treating TIAs.The technology of TCD can provide a new indicator for clinic selection of reasonable treatment and evaluation of ef ect.