超声射频信号技术分析维持性血液透析患者颈动脉弹性功能的研究

摘要

目的：应用超声射频信号血管内中膜分析(QIMT)、动脉硬度分析(QAS)技术研究维持性血液透析患者颈动脉血管功能进行评估，探讨其在透析患者。方法选择在我院维持性血液透析患者67例，按透析过程中有无低血压的发生将透析组患者分为透析低血压组33例和非低血压组34例，另选取30例健康者为对照组，分别接受颈动脉超声检查，获取颈总动脉内中膜厚度(IMT)、僵硬度系数(α、β)、脉搏波速度(PWV)。结果与对照组相比较，透析组血管僵硬度参数IMT、PWV、α、β均增高(<0.05)；透析低血压组血管僵硬度参数IMT、PWV、α、β较非低血压组增高更为显著(<0.05)。结论透析低血压是透析患者心血管功能的重要影响因素，其血管弹性功能减低更为明显。超声射频技术血管内中膜分析(QIMT)、动脉硬度分析(QAS)技术可以早期获取并分析维持血液透析患者颈动脉弹性功能。%Objective To study on the carotid arterial elasticity in the patients with maintenance hemodialysis (MHD) by using quality intima-media thickness (QIMT),quality arterial stiffness (QAS).Methods 67 patients with maintenance hemodialysis in our hospital were selected,and they were divided into hypotesion group (n=33)and non-hypotesion group (n=34) according to whether or not hemodialytic hyposion was present.30 healthy volunteers were selected as a control group.Ultrasound examination for the carotid artery was performed and some parameters were obtained,such as intima-meida thickness (IMT),stiffness index (α and β),pulse wave velocity (PWV). Results Compared with the control group,vascular stiffness parameter IMT, α,βand PWV were all increased ( <0.05);IDH group than in N-IDH group increased more significantly ( <0.05).Conclusion Hypotesion was one of the important factor which could influent the vascular sclerosis and,QIMT,QAS technology can be used in patients with maintenance hemodialysis to evaluate vascular sclerosis and carotid arterial elasticity.