原发性胃肠道T细胞淋巴瘤26例临床病理特征及预后分析

摘要

目的：研究原发性胃肠道 T细胞淋巴瘤临床病理特征及预后相关因素。方法：回顾性分析2008年1月至2013年12月期间我院收治的胃肠道 T细胞淋巴瘤患者26例的临床资料。结果：本组26例中，男∶女＝1．17∶1，首发症状以消化道症状为主（42．3％），病变部位以肠道为主（73．1％）。患者3年生存率为15．4％，生存因素分析表明年龄、首发症状、病变直径、LDH 升高与否、临床分期因素与预后相关（P＜0．05）。结论：原发性胃肠道T 细胞淋巴瘤是一组预后不良的疾病，其预后与年龄、首发症状、病变直径、LDH 升高与否、临床分期因素等相关。%Objective:To investigate clinicopathological features and prognosis in patients with primary gastrointestinal T cell lymphoma. Methods:The clinical data of 26 patients with primary gastrointestinal T cell lymphoma were analyzed retrospectively from Jan 2008 to Dec 2013. Results:Among the 26 cases,the male/female ratio was 1.17:1,and the first syndrome was major in gastrointestinal discomfort. The intestine was the main location of lymphoma. The overall 3-year survival rate was 15.4%. And survival analysis resulted in that age,first syndrome, lesion size,LDH elevation,clinical stage could be its main prognostic factors. Conclusion:Primary gastrointestinal T cell lymphoma is a group of diseases with poor prognosis,and age,first syndrome,lesion size,LDH elevation,clinical stage could be its main prognostic factor.