肌酐检测方法及常见药物对肌酐检测干扰的研究进展

摘要

血清肌酐的检测有多种方法,每种方法的特异性和抗干扰能力均不同,由此造成不同临床实验室血清肌酐测定结果出现差异.此外,药物对肌酐测定的干扰问题受到越来越多的关注,临床上很多常见的药物均会导致肌酐测定出现假性结果,且同种药物会因不同的检测方法而出现不同的干扰方向.文章对肌酐的检测方法及干扰肌酐检测结果的常见药物作一综述.%There are various methods for the determination of serum creatinine,and the specificities and anti-interference performance of methods are different. The determinations of serum creatinine in different clinical laboratories have biases. The interference of common drugs on creatinine determination has been drawn more and more attention. Many commonly-used drugs can lead to false results on creatinine determination. The interference directions vary from different methods of creatinine determination. The methods for creatinine determination and the interference of common drugs on creatinine determination are reviewed.