目的：了解老年心脑血管病患者阿司匹林抵抗（AR）的发生率，分析相关危险因素。方法选取老年缺血性心脑血管病患者150例，测定其血小板聚集率。将患者分为阿司匹林敏感（AS）组和非 AS 组。分别测定患者年龄、性别、红细胞计数、糖化血红蛋白等指标并比较组间差异。结果 AR 发生率为3．3％；阿司匹林半抵抗发生率为32．7％。非 AS 组吸烟百分比、红细胞计数及糖化血红蛋白水平明显高于 AS 组，差异有统计学意义（P ＜0．05）。结论吸烟、红细胞计数及糖化血红蛋白水平升高是 AR 发生的危险因素。%Objective To investigate the incidence of aspirin resistance in the old and its clinical risk factors . Methods One hundred and fifty cases of old people with cardio - cerebrovascular diseases were investigated in this study .Platelet aggregation was detected .The patients were divided into AS group and non AS group .The incidence of AR and ASR among the study and the influential factors associated with AR and ASR were analyzed .Results 3 .3%of these patients were AR and 32 .7% were ASR .Compared with the AS group ,the proportion of smoking ,RBC counts and the HbA1c were increased statistically significant in the non-AS group(P< 0 .05) .Conclusion The pri-mary risk factors of AR are smoking ,increased RBC counts and HbA1c .
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