性激素水平对老年男性高危性行为的影响

摘要

Objective To investigate the impacts of serum levels of testosterone and testosterone/estradiol ra-tio on high-risk sexual behavior in elderly males (≥60 years old) .Methods 80 cases among 432 elderly male patients (≥60 years old) with sexually transmitted diseases (STD) ,diagnosed in Dermatology and STD Department of the Thirteenth People′s Hospital (original Chongqing Railway Hospital ) in 2009-2012 ,were randomly selected as ob-servation group ,another 38 healthy elderly males were randomly selected as control group .Serum testosterone and estradiol were detected ,and situations of extramarital sex ,frequency of extra-marital sex ,numbers of extra-marital sexual partners ,spouses ,and sexual life with spouses were investigated .All data were arranged and analyzed .Re-sults There were significantly differences of serum testosterone level and testosterone/estradiol ratio between the two groups (P<0 .05) .There were no significantly differences of serum levels of testosterone and estradiol between patients with different frequency of extra-marital sex ,numbers of extra-marital sexual partners (P>0 .05) .Conclu-sion High levels of serum testosterone and testosterone/estradiol ratio might be the endocrinology foundation of high-risk sexual behavior and the spread of STD in elderly males .There might be with individual differences of the responses of frequency of extra-marital sex and numbers of extra-marital sexual partners to levels of testosterone and testosterone/estradiol ratio .%目的探讨血清睾酮水平及睾酮/雌二醇比值对老年（≥60岁）男性高危性行为的影响。方法随机选取2009～2012年在重庆市第十三人民医院皮肤性病科门诊确诊的432例老年（≥60岁）男性性传播疾病（STD）患者中的80例作为观察组，另随机选取在重庆市第十三人民医院进行年度体检的38例老年健康男性作为健康对照组，检测血清睾酮及雌二醇水平，询问调查研究对象有无婚外性行为及次数、婚外性伴数、有无配偶，以及有配偶者同配偶的性生活情况，将上述各项检测及调查数据进行整理并分析。结果两组血清睾酮水平、睾酮/雌二醇比值比较，差异有统计学意义（P＜0．05）。结论较高的血清睾酮水平及睾酮/雌二醇比值是老年男性高危性行为及其传播STD的内分泌学基础，其婚外性行为次数及婚外性伴数对睾酮水平及睾酮/雌二醇比值的反应存在着个体差异。