女性不孕症患者的激素指标特征与临床诊断价值分析

摘要

目的：研究女性不孕症患者的促卵泡激素（FSH）、泌乳素（PRL）、雌二醇（E2）、促黄体生成素（LH）等指标特征对于临床诊断价值。方法选取2011年2月至2013年2月在该院治疗的128例不孕症患者为研究对象，根据月经情况分为月经正常组40例和月经紊乱组88例，选取同期健康体检女性100例为对照组。所有研究对象在月经2～3 d抽空腹静脉血5 mL ，分离血清，应用全自动化学发光检测仪进行 FSH、PRL、E2、LH等激素水平进行测定，比较月经正常组、月经紊乱组和对照组患者的FS H、PRL、E2、L H等激素水平。分析FS H、PRL、E2、L H等激素对不孕症的影响。同时随访比较不孕症患者治愈后与对照组FSH、PRL、HL、E2等激素水平情况。结果月经紊乱组患者的FS H、PRL、L H激素水平明显高于对照组，差异具有统计学意义（ P＜0．05）；E2激素水平明显低于对照组，差异具有统计学意义（P＜0．05）。月经正常组患者的 FSH、PRL、LH、E2等激素水平与对照组比较，差异无统计学意义（ P＞0．05）。不孕症患者治愈后与对照组比较，两组的 FS H、PRL、E2、L H等激素水平差异无统计学意义。结论女性不孕症患者的FS H、PRL等激素的测定对临床上诊断不孕症具有重要意义。同时也是监测不孕症治疗效果的一种重要方法。%Objective To study the FSH (follicle stimulating hormone) ,PRL (prolactin) ,E2 (estradiol) ,LH (luteinizing hormone ) and other hormone characteristics and clinical diagnostic value of female infertility patients . Methods 128 cases of infertility patients selected form February 2011-February 2013 in our hospital for the study , divided into normal group with 40 cases and menstrual disorders group roith 88 cases ,according to the menstrual pe-riod and another 100 cases of physical health examination women were selected as the control group .All the research objects were taken abdominal venous blood 5 mL 2-3 days in menstruation ,separation of serum ,application of full automatic chemiluminescence detector to determine FSH ,LH ,PRL ,E2 ,hormone levels compared .Compare FSH , PRL ,E2 ,LH hormone levels ,etc in normal menstruation ,menstrual disorders group and control group .Analysis of the influence of FSH ,LH ,PRL ,E2 hormones on infertility .Meanwhile cure infertility patients were followed up after comparison with the control group ,FSH ,PRL ,HL ,E2 hormone levels and other conditions .Results After disorder group of patients FSH ,PRL ,LH hormone levels were significantly higher ,the difference was statistically significant (P<0 .05);E2 hormone levels were significantly lower than the control group ,the difference was statistically signifi-cant (P<0 .05) .Group of patients with normal menstrual FSH ,PRL ,LH ,E2 and other hormone levels compared with control group ,the difference was not statistically significant (P>0 .05) .After cure infertility compared with the control group ,no difference was observed in FSH ,PRL ,E2 ,LH and other hormone levels .Conclusion The determi-nation of FSH ,PRL and other characteristics of female infertility patients had important clinical value ,with could provide significant basis for the clinical diagnosis and treatment of infertility patients .