超声造影在乳腺癌腋窝淋巴结良恶性鉴别诊断中的价值

摘要

目的：评价超声造影在乳腺癌患者腋窝淋巴结的良恶性鉴别诊断中的价值。方法对该院确诊为乳腺癌的50例患者的72枚腋窝肿大淋巴结的临床资料进行回顾性分析。根据病理检查结果将72枚淋巴结分为转移组与良性组，分别为42枚与30枚，收集常规超声检查与超声造影检查的结果进行分析。结果转移组淋巴结的长短径之比(L/S)明显较良性组小(P <0.05)；两组间的血流分布特点比较，差异有统计学意义(P <0.05)，门型血流在良性组较多，而周围及混合型血流在转移组较多；两组的超声造影强化模式比较，差异有统计学意义(P <0.05)，良性组多为中央均匀强化，而转移组多为周围或混合型强化；超声造影强化时间在转移组明显多于良性组(P <0.05)。结论超声造影检查可以很好地补充常规超声检查的不足，明显提高超声检查鉴别乳腺癌良恶性腋窝淋巴结的效能。%Objective To evaluate the value of contrast-enhanced ultrasound in the differentiation diagnosis of benign and malignant axillary lymph nodes in breast cancer.Methods The clinical data in 72 enlarged axillary lymph nodes from 50 patients with breast cancer were analyzed retrospectively.According to the lymph node pathological re-sults,72 axillary lymph nodes were divided into the benign group(n=30)and the metastatic group (n=42).The re-sults of conventional ultrasound examinations and contrast-enhanced ultrasound examination were collected and ana-lyzed.Results The long diameter/short diameter(L/S)ratio in the metastatic group was significantly less than that in the benign group (P < 0.05 ).The blood flow distribution patterns had statistical difference between the two groups (P <0.05).In the benign group,the main blood flow pattern was portal type and the main contrast enhance-ment pattern was central homogeneous enhancement,while in the metastatic group,the main blood flow patterns were peripheral or mixed types and the main contrast enhancement patterns were peripheral or mixed type,the differences between the two groups were statistically significant.The contrast enhancement time in the metastatic group was greater that that in the benign group (P <0.05).Conclusion The contrast-enhanced ultrasound imaging can better replenish the insufficiency of convention ultrasound imaging and significantly improves the ability to identify benign and malignant axillary lymph nodes in breast cancer.