育龄男男性行为人群梅毒感染情况及影响因素研究∗

摘要

Objective To study the TP infection situation and its influencing factors among men who have sex with men(MSM)in their childbearing period.Methods 434 cases of MSM were selected as the study group and 521 cases men of reproductive age were selected as the control group.Two groups performed the questionnaire survey and blood sample collection for conducting TP test.The blood sample was preliminarily screened by the rapid plasma re-gain(RPR),and confirmed by treponema pallidum particle assay(TPPA),and the TP antibody titer was detected by tolulized red unheated serum test(TRUST).The mass prevalence of TP infection was compared among groups,and the influencing factors were analyzed.Results Of 438 MSM,83 cases (18.9%)were positive for RPR,54(12.3%) were positive for TPPA,and 14(3.2%)cases had TRUST>1∶8;there were 62 cases(14.2%)of TP accumulative infection in the study group,which was higher than that in the control group(P <0.05),the TP accumulative infec-tion rate had statistically significant difference among different age groups(P <0.05).The sexual partner,sexual in-tercourse mode and condom use had statistical differences between the TP infection group and the non-infection group (P <0.05).The Logistic aggression revealed that age,sexual partner,condom use were the independent influencing factors of TP infection.Conclusion The MSM population has higher TP infection rate,and age,risky sexual behavior are the risk factors of TP infection.%目的：研究育龄男男性行为(MSM)人群梅毒(TP)感染情况及影响因素。方法对其进行问卷调查并采集静脉血。梅毒快速反应试验(RPR)进行初筛,梅毒螺旋体凝集试验(TPPA)确诊,甲苯胺红血清反应素试验(TRUST)检测 TP 抗体滴度,分组比较 MSM 群体感染率并分析 TP 感染的影响因素。结果438例研究对象RPR 阳性83例(18.9%),TPPA 阳性54例(12.3%),TRUST≥1∶8患者14例(3.2%)；研究组 TP 累计感染62例(14.2%),明显高于对照组(P <0.05),不同年龄组间 TP 累计感染率比较,差异有统计学意义(P <0.05)；TP 感染组与阴性组在性伴侣、性交方式、安全套使用方面比较,差异有统计学意义(P <0.05),逐步 Logistic 回归分析年龄、性伴侣、安全套使用是独立的影响因素。结论MSM 群体 TP 感染率较高,高龄、风险性行为是 TP 感染的危险因素。