[Objective] To observe the cure effect of photodynamic therapy(PDT) combined with TCM on verruca acuminata. [Method] Select 80 cases of verruca acuminata, divide them into control group and treatment group, n=40 for each; the control one only took LE D-IB PDT therapeutic apparatus, the treatment one added with TCM on the base of control one; Observe their cure effects and side effects. [Result] The effective rate was 97.5% for treatment group, and 88.5% for control one, the treatment one was better than other one; there ’re 2 cases in each group respectively who had slight red and swol en skin of the il umination part, without side effects of erosion, ulcer, infection or scar;the recurrence rates were respectively 2.5% and 12.5% for both groups, the difference had statistical meaning. [Conclusion] PDT combined with TCM treating verruca acuminata had high cure rate, low recurrence rate, little side effects and high safety, without influencing patients ’life quality, with good compliance, worth clinical broad popularization.%[目的]观察光动力疗法联合中药治疗尖锐湿疣的疗效。[方法]选择于我院门诊就诊并确诊为尖锐湿疣的80例患者，分为对照组和治疗组各40例，对照组单纯采用LED-IB型光动力治疗仪，治疗组在对照组基础上加用中药，观察比较两组疗效及不良反应情况。[结果]治疗组与对照组有效率分别为97.5%和88.5%，治疗组疗效优于对照组（P＜0.05）；两组各有2例患者光照部位出现轻度红肿，均无糜烂、溃疡及感染、疤痕形成等不良反应；治疗组和对照组复发率分别为2.5%和12.5%，差异有统计学意义（P＜0.05）。[结论]光动力疗法联合中药治疗尖锐湿疣治愈率高，复发率低，不良反应小，安全性高，不影响患者的生活质量，患者依从性好，值得临床广泛推广。
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