目的 了解北海地区居民血尿酸水平及相关指标.方法 对5 400例健康体检者的血尿酸水平及相关指标的测定结果进行统计分析.结果 男性平均血尿酸水平为(420.82±87.53) μmol/L,女性为(309.09±71.20) μmol/L,男性高尿酸血症患病率为47.81%,女性为24.40%,男性均显著高于女性(P<0.01).男性高尿酸血症的患病率随年龄的增长而降低,20岁年龄组与50岁以上各中老年年龄组之间有统计学差异(P<0.05或P<0.01);女性患病率随年龄的增长而升高,20、30、40岁青壮年年龄组与50岁以上各中老年年龄组之间有统计学差异(P<0.05或P<0.01).高尿酸血症组与正常组比较,男性组与女性组比较,高血压发病率及体重超标发生率均有统计学差异(P＜0.05或P<0.01).结论 北海地区居民血尿酸水平和高尿酸血症的患病率均高于内地其他地区的调查结果,男性高尿酸血症的患病率随年龄的增长而降低,女性随年龄的增长而升高.高尿酸血症患者更容易伴发高血压、超重.%Objective To investigate the blood uric acid level of inhabitants in Beihai and to explore the correlation between hyperuricemia and blood biochemical examination, hypertention.Methods 5 400 inhabitants in Beihai underwent physical examinations and the levels of blood uric acid (BUA) and the related indicators were statistically analyzed.Results The mean level of BUA was (420.82 ±87.53) μmol/L in males and (309.09 ±71.20) μmol/L in females.The prevalence of hyperuricemia was 47.81％ in the male and 24.40％ in the female, with a significantly higher prevalence of hyperurieemia in the male (P ＜ 0.01 ).In the male, the prevalence of hyperurieemia declined with age, and there was statistical difference between young ( aged 20) groups and middle/elderly ( aged over 50) groups ( P ＜ 0.05 or P ＜0.01 ); in the female, the prevalence of hyperuricemia increased with age, and there was statistical difference between the young/prime groups and the middle - aged/elderly groups ( P ＜ 0.05 or P ＜ 0.01 ).There were statistical differences in the prevalence of excessive body mass index (BMI) and hypertension between hyperuricemia group and normal group as well as between males and females (P ＜ 0.05 or P ＜ 0.01 ).Conclusion The mean of BUA and the prevalence of hyperuricemia in the inhabitants in Beihai were higher than those in other districts in Mainland China.In the male, the prevalence of hyperuricemia declined with age, while in the female, it increased with age.Patients with hyperuricemia are more susceptible to complications such as hypertension and overweight.
展开▼
