超声造影在经皮微波消融治疗肝癌术中的应用价值

摘要

Objective To assess the application of contrast-enhanced ultrasonography ( CEUS ) in patients with liver cancer during the operation of percutaneous microwave ablation ( PMWA) .Methods A total of 100 patients with 120 focal liver lesions were treated with ultrasound-guided PMWA, of which 50 patients with 59 focal liver lesions per-formed CEUS guidance ( an untrasonography group ) , and another 50 patients with 61 focal lesions did not underwent CEUS ( the control) .All patients were followed up for 1 month after treatment.Canter relapse were determined through enhanced CT or CEUS in focal lesions and surrounding areas.Results The recurrence rate of the untrasonography group was 8%(4/50), which was lower than the control 22%(11/50) (χ2 =3.84,P=0.04995).The inactivation rate of tumor was 93.2%(55/99), which was higher than the control 72.1%(44/61) (χ2 =9.24, P=0.002).Conclusion The use of CEUS in PMWA can increase efficiency and reduce relapse rate.%目的：评价超声造影（ contrast－enhanced ultrasonography，CEUS）在经皮微波消融（ pereutaneous micro-wave ablation，PMWA）治疗肝癌术中的应用价值。方法100例（120个病灶）超声引导下进行肝癌微波消融术，其中50例患者（59个病灶）行超声造影引导（造影组），50例患者（61个病灶）未行超声造影引导（对照组），术后随访1个月，以原治疗病灶区域内或周边增强CT或CEUS发现病灶为肿瘤复发。结果造影组复发率8％（4／50）低于对照组复发率22％（11／50）（χ2＝3．84，P＝0．04995）；造影组瘤体灭活率93．2％（55／59）高于对照组瘤体灭活率72．1％（44／61）（χ2＝9．24，P＝0．002）。结论 PMWA术中使用超声造影可以提高治疗效果，减少复发率。