产前超声筛查在胎儿神经管畸形中的价值探讨

摘要

Objective To evaluate the clinical value of standardized ultrasound screening for fetal central nerve system abnormalities.Methods During the period of Feb.2008 and Feb.2014 3 056 pregnancy women were subjected to ultrasound screening in our hospital.The structures,such as the head and spine were scanned in detail.Results Eighty-seven fetus with fetal central nerve system abnormalities were ex-amined prenatally by ultrasound and each showed typical imaging feature.Among these cases,there were 32 cases of hydrocephalus,5 cases of holoprosencephaly,11 cases of anencephaly,1 cases of iniencephaly, 8 cases of choroid plexus cysts,3 cases of Dandy-Walker complex,6 cases of cephalocele,19 cases of spina bifida and 2 cases of scoliosis.Conclusion Standardized ultrasound screening is of great value to screen fe-tal abnormality,which can reduce the risk of medical treatment in fetal abnormality screening.%目的：探讨产前超声筛查在胎儿神经管缺陷中的应用价值。方法参考国际妇产超声学会（ISUOG）操作规范，对2008年2月－2014年2月在新疆医科大学第一附属医院就诊的3056例孕妇进行了产前超声筛查，系统检查胎儿头颅、脊柱等结构，对其病例资料进行回顾性分析。结果3056例胎儿中共检出胎儿神经管缺陷87例，其中脑室扩张32例，前脑无裂畸形5例，无脑儿11例，露脑畸形1例，脉络膜囊肿8例，Dandy-walker 畸形3例，脑脊膜膨出4例，脑膜脑膨出2例，脊柱裂19例，半椎体畸形2例。结论产前超声筛查能够最大限度地检出胎儿神经管畸形，对减少漏诊率、降低医疗风险具有重要的临床意义。