Objective To investigate the factors of aortic reconstruction and left atrial remodeling in essen-tial hypertension.Methods According to condition of the aorta and left atrium,924 cases of essential hy-pertension divided into four groups:the aorta and left atrial diameter enlarged group,the aorta enlarged group,the left atrial enlarged group,the aortic and left atrial diameter normal group.Left atrial systolic diameter (LADs),aortic sinus diameter,left ventricular end-diastolic diameter (LVEDd),diastolic left ventricular septal and posterior wall thickness (IVSd ,LVPWd)were measured and the left ventricular mass index (LVMI)were calculated.Results The age (57.52±14.70)years,LVMI (138.61±43.02)g/m2, systolic blood pressure (149.79±16.57)mmHg,diastolic blood pressure (95.91±15.34)mmHg,disease duration (8.79±6.50)were greater in the aorta and left atrial diameter enlarged group than those in aorta and left atrium normal group (P<0.05).The age (59.53±12.22)years,systolic blood pressure (141.93± 15.89)mmHg,disease duration (7.75 ± 6.74)were greater in aortic widened and left atrial diameter normal group than those in normal aorta left atrium normal group (P<0.05).The age of aorta broadening and the left atrial normal group (59.53±12.22)was greater than the age of the aorta normal left atrial en-largement group (P <0.05).The body mass index (BMI)(27.39±3.48)kg/m2,LVMI (129.97±40.34) g/m2,diastolic blood pressure (92.94±15.94)mmHg in normal aortic and left atrial diameter enlarged group ,were greater than those in normal left atrial and normal aorta group (P <0.05).LVMI (129.97± 40.34)g/m2 in the left atrium enlargedand normal aorta group were higher than those in normal aorta wid-ened and left atrium normal group (P <0.05).ROC curve shew that in the many factors affecting the aortic reconstruction patients,ages occupied the largest area under the curve which was 0.68;while among the many fac-tors that affect patients with left atrial remodeling,LVMI occupied the largest area under the curve which was 0.71.Conclusion Age and LVMI were the main factors of the remodeling in aorta and left atrium.%目的：探讨原发性高血压患者主动脉重构和左心房重构相关的诸因素变化特点及相互关系。方法选择924例原发性高血压患者，根据主动脉及左心房是否重构扩大分为主动脉增宽左心房增大组、主动脉增宽左心房正常组、左心房增大主动脉正常组、主动脉正常左心房正常组，分别测量各组患者的左房收缩末期内径（LADs）、主动脉窦部内径、左心室舒张末期内径（LVEDd）、舒张期室间隔及左室后壁厚度（IVSd、LVPWd），并计算左心室心肌重量指数（LVMI）等指标。结果主动脉增宽左心房增大组患者的年龄（57．52±14．70）岁、LVMI （138．61±43．02）g／m2、收缩压（149．79±16．57）mmHg、舒张压（95．91±15．34）mmHg、病程（8．79±6．50）a均大于主动脉正常左房正常组（P ＜0．05）。主动脉增宽左房正常组患者的年龄（59．53±12．22）岁、收缩压（141．93±15．89） mmHg、病程（7．75±6．74）a大于主动脉正常左心房正常组（P ＜0．05），主动脉增宽左房正常组患者年龄（59．53±12．22）岁大于主动脉正常左房增大组患者（P ＜0．05）。主动脉正常左心房增大组患者的体质指数（BMI）（27．39±3．48）kg／m2、LVMI（129．97±40．34）g／m2、舒张压（92．94±15．94）mmHg 均大于主动脉正常左房正常组（P ＜0．05），主动脉正常左心房增大组患者 LVMI（129．97±40．34）g／m2大于主动脉增宽左房正常组（P ＜0．05）。ROC曲线示，在影响患者主动脉重构的众多因素中，年龄所占曲线下面积最大（0．68），在影响患者左心房重构的众多因素中，LVMI所占曲线下面积最大（0．71）。结论年龄和 LVMI分别是主动脉重构和左房重构的最重要影响因素。
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