镁在脑损伤脑水肿中的作用

摘要

Mg++，the important intracellular catholyt e in human body,taking a part in the metabolism of sugar,fat,and protein,plays an important role in metabolism and regulation of the brain.Abnormal free Mg ++may lead to pathological change of energy metabolism,permeability of the mem branion and lipid metabolism.Brain injury may be accompanied with the loss of M g++,and deficiency of Mg＋＋ may induce brain edema or worse one.Re asonable raising Mg++in vivo may reduce secondary brain injury to some ext ent.%镁(Mg++)是人体内重要的细胞 内 阳离子，作为多种酶的辅助因子参与糖、脂肪及蛋白质的代谢，在脑组织中具有重要的代谢 和调节功能。游离Mg++的异常可导致能量代谢、膜离子通透性、脂质代谢等方面的病 理生理变化。大多数脑损伤常伴有Mg++的丢失，摄取Mg++不足可导致或加重脑 水肿，补充或适当提高体内Mg++的含量对脑损伤具有一定的保护作用。