健康促进生活方式与亚健康危险性的巢式病例对照研究

摘要

Objective To explore the relationship between the occurrence of sub-health and health promotion lifestyle in Guangdong province to provide epidemiological evidences for prevention of sub-health. Methods A 1:1 nested case-control study was carried out involving 133 cases from the cohort study paired with 133 control case matched for gender and age. Results The univariate conditional logistic regression model showed no significant association of marital status, education level, or body mass index with the occurrence of sub-health, but a significant correlation was found between lifestyle and sub-health with an odd ratio of 5.90 (95%CI:3.12-11.16, P=0.000). Analysis of the multivariate conditional logistic regression model on the 6 subscales of health promotion lifestyle showed that stress management was significantly correlated with the occurrence of sub-health with an odd ratio of 4.00 (95%CI:1.54-10.40, P=0.004). Conclusion A unhealthy lifestyle, especially in terms of stress management, is the major risk factor contributing to the occurrence of sub-health.%目的：探讨广东地区人群健康促进生活方式与亚健康发生之间的关联，为亚健康的预防提供依据。方法采用巢式病例对照研究方法，从队列中获得由健康状态转化为亚健康状态133例，按1∶1的比例分别匹配以性别相同、年龄相近的对照。结果单因素条件logistic回归分析发现婚姻状况、教育程度及体质指数差异未见显著，健康促进生活方式与亚健康的发生有显著性意义，OR值为5.90（95%CI为3.12~11.16，P=0.000）。对健康促进生活方式中的六个维度进行多因素条件logistic回归分析，发现压力管理的贡献作用有统计学关联，OR值为4.00（95%CI为1.54~10.40，P=0.004）。结论不良的健康促进生活方式是亚健康发生的重要危险因素之一，其中以压力管理能力的作用较为突出。