乙二胺N,N-二(4-乙酰胺苯甲酸)二乙酸配合物的合成、表征与性能研究

摘要

通过乙二胺四乙酸二酐与对氨基苯甲酸的酰化反应合成了乙二胺N,N-二(4-乙酰胺苯甲酸)二乙酸(H4L),并以此为配体分别与稀土离子Sm3+、Gd3+、Eu3+和过渡金属离子Mn2+、Fe3+组装得到系列配合物.用红外光谱、紫外-可见光谱、元素分析及热重-差热分析对配合物进行了组成与结构表征的分析,配合物的组成为M(HL)·3H2O(M=Sm3+,Eu3+,Gd3+,Fe3+)或者M(H2L)·3H2O(M=Mn2+).配合物Gd(HL)·3H2O的荧光发射光谱中没有离子特征谱图,而配合物Eu(HL)·3H2O在618 nm处5D0→7F3跃迁的发射峰最强.配合物Cd(HL)·382O的弛豫率为7.43 mmol/(L·s),体外弛豫性能明显提高.%The ligand ethylenediamine -N, N -di (4 -acetamide benzoic acid) -diacetate (H4L) is synthesized by acylation reaction of ethylenediamine tetraacetic acid dianhydride and p - amniobenzoic acid.A series complexes were prepared after the reaction of the ligand with rare earth ions Gd3 +, Sm3 + , Eu3 + and transition metal ions Mn2 +, Fe3 + respectively.The complexes were characterized by IR, UV - Vis, element analysis and TG - DTA.The results showed that the chemical composition of the complexes is confirmed to be M(HL) ·3H2O( M = Sm3+ ,Eu3+ ,Gd3+ ,Fe3+ )or M( H2L) · 3H2O( M = Mn2+ ).The fluorescence emission spectra of the complexes were measured and investigated, there is no characteristic emission peak of ion in fluorescence emission spectrum for Gd(HL) · 3H2O, while emission peak of 5D0 →7F3 transition is the strongest at 618 nm for the complex Eu(HL) · 3H2O.The longitudinal relaxivity R1 of Gd complex was 7.43 mmol/( L · s) ,which was more greater than small molecular weight complex Gd - DTPA.