目的：对临沂市健康人群和腹泻病人诺如病毒带毒率进行调查，分析诺如病毒隐性感染组别与腹泻患者感染组别的关系。方法以从事餐饮行业健康人群和门诊腹泻病人为调查对象，于3～12月份对322名健康人群和303份门诊腹泻病人进行粪便标本的采集。并对采集的标本进行诺如病毒GⅠ组和GⅡ组的Real‐time PCR检测，对检测结果进行分析。结果①322份健康人群粪便标本中5份标本为诺如病毒阳性，阳性率为1．55％，其中，3份为GⅠ组阳性，2份为GⅡ组阳性；②303份门诊腹泻病人粪便标本中9份标本为诺如病毒阳性，阳性率为2．97％，其中，1份为GⅠ组阳性，8份为GⅡ组阳性。结论本地区健康人群诺如病毒带毒率和与本地区当年门诊腹泻患者感染诺如病毒的比例密切相关，而本地区健康人群携带诺如病毒的组别与本地区当年腹泻患者所感染的毒株组别是有差别的。%Objective To investigate norovirus‐carrying rate among healthy people and patients with diar‐rhea in Linyi ,and to analyze norovirual gene group relationship between the latent infection of healthy people and patients with diarrhea in Linyi .Methods 322 healthy people working in the food and beverage industry and 303 patients with diarrhea from hospital were surveyed from March to December .625 re‐spondent stool specimens w ere collected and detected using real time RT‐PCR for norovirus GⅠand GⅡ , and the results were analyzed statistically .Results ①There were 5 stool specimens that were detected no‐rovirus from 322 healthy people ,and the positive rate was 1 .55% ,including 3 norovirus GⅠ and 2 noro‐virus GⅡ ;②There were 9 stool specimens that were detected norovirus from 303 patients with diarrhea , and the positive rate was 2 .97% ,including 1 norovirus GⅠ and 8 norovirus GⅡ .Conclusion There was closely related between the latent infection rate of healthy people and positive rate of patients with diarrhe‐a .However ,there was a norovirual gene group difference between healthy people and patients with diar‐rhea .
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