经椎间孔周围神经电刺激与脊髓电刺激治疗带状疱疹神经痛的疗效对比

摘要

目的 观察经椎间孔周围神经电刺激(PNS)与脊髓电刺激(SCS)治疗带状疱疹神经痛的疗效.方法 采用随机数字表法将2015年1月至2016年1月我院收治的64例带状疱疹神经痛患者分为PNS组及SCS组,2组患者分别给予14 d经椎间孔PNS或SCS短时程治疗.于术前、术后次日、术后1周、2周、1个月、2个月时采用视觉模拟评分(VAS)及匹兹堡睡眠质量指数(PSQI)评分对患者进行疗效评定.结果 术前及术后2个月,PNS组的VAS评分分别为(8.4±1.6)分、(1.4±1.0)分,PQSI评分分别为(16.1±2.1)分、(5.8±1.3)分;SCS组的VAS评分分别为(8.6±1.8)分、(2.9±1.2)分,PQSI评分分别为(15.6±2.3)分、(7.5±1.5)分.术后PNS组及SCS组疼痛均明显缓解,睡眠质量明显改善,不同时间点与术前VAS评分及POSI评分比较差异具有统计学意义(P<0.05).2组在术后相同时间点比较,PNS组VAS及PQSI评分均优于SCS组,差异具有统计学意义(P<0.05).结论 经椎间孔PNS在降低带状疱疹神经痛和改善睡眠质量方面优于SCS.%Objective To compare the effects of transforaminal peripheral nerve stimulation(PNS) and spinal cord stimulation(SCS) in treatment of postherpetic neuralgia.Methods A total of 64 patients with postherpetic neuralgia in our hospital from January 2015 to January 2016 were divided into PNS group and SCS group according to random number table.Both two groups were treated with PNS or SCS for 14 days,respectively.Visual analogue scale(VAS) and piasburgh sleep quality index(PSQI) were adapted to assess the effects at the different time of preoperation, postoperation 1 day,1 week,1 month,2 months.Results At the preoperation and 2 months postoperation,in PNS group,the VAS were (8.4±1.6) and (1.4±1.0),the PSQI were (16.1±2.1) and (5.8±1.3),respectively;meanwhile in the SCS group,the VAS were (8.6±1.8) and (2.9±1.2),the PSQI were (15.6±2.3),(7.5±1.5),respectively.Obviously,the VAS and PQSI at different follow-up stages were improved after transforaminal PNS or SCS treatment, the differences were signicant(P<0.05).Moreover,the PNS group had lower VAS and higher PQSI compared with the SCS group at different follow-up stages,the differences were signicant(P<0.05).Conclusion The transforaminal PNS achieved satisfying outcomes on pain relief and quality of sleep improvements for the postherpetic neuralgia patients,which was superior to that of the SCS.