目的：了解近年散发性戊型肝炎的发病特点。方法回顾性分析2009年1月～2012年12月收治的305例戊型肝炎患者的流行病学和临床资料。结果本研究纳入男性221例（72.7%），女性84例（27.3%），平均年龄57.8岁；在2009年、2010年、2011年和2012年，40～59岁年龄组发病率分别为33.3%、48.7%、46.3%和50.9%，除2009年外，均明显高于其他年龄组（P<0.05）；大于60岁年龄组患者血清胆红素峰值为（254.21±103.9）μmol/L，明显高于其他年龄组患者（P<0.05）。结论散发性戊型肝炎呈发病率增加和年轻化趋势，需要加强监管和治疗。%Objective To explore the epidemiologic and clinical characteristics of patients with sporadic hepatitis E in recent years. Methods A total of 305 patients with hepatitis E from Jan. 2009 to Dec. 2012 in our hospital were included. The epidemiologic and clinical features of patients were analyzed retrospectively. Re-sults There were 221 male (72.7%)and 84 female (27.3%)patients were included in this study,with an average age of 57.8;The incidence in patients aged from 40 to 59-yr-old in 2009,2010,2011 and 2012 were 33.3%, 48.7%,46.3% and 50.9%,all but 2009 were higher than those in patients younger than 40 or older than 60(P<0.05);The serum bilirubin levels at peak in patients older than 60 were 254.21±103.9μmol/L,much higher than those in patients younger than 60(P<0.05). Conclusions The incidence of sporadic viral hepatitis E is increasing in recent years with a trend of younger age of the patients. More attention should be put into the surveillance and treatment of this disease.
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