In order to probe into the effects of self-controlled exercising on lymphocyte subsets in malignant tumor patients after surgery, the authors selected 40 new students (17 male students and 23 female students) from Shanghai Cancer Rehabilitation School as their test subjects, whose average age was 57.50±6.84, whose average cancer age was 1.50±0.77. The types of sickness were respectively digestive system cancer, breast cancer, other types of ma-lignant tumors (lung cancer, ovarian cancer etc). Guided by specialists, the patients learnt self-controlled exercising for 3 weeks, and then maintained self-controlled exercising for 24 weeks, at an average exercising frequency of 5 days a week, and a daily exercising duration of 2 hours. The authors tested the contents of cells CD3+, NK and NKT in the peripheral blood of the patients before the experiment, in weeks 12 and 24 respectively, and revealed the fol-lowing findings: 1) in week 24 after the experiment, the content of lymphocyte CD3+ increased significantly (P<0.01);2) in week 12 after the experiment, the content of cell NKT increased significantly (P<0.05), and in week 24, it was significantly higher than that measured before the experiment (P<0.01) and that measured in week 12 (P<0.05) respectively; 3) in week 12 after the experiment, the content of NKT was significantly higher than that measured before the experiment (P<0.05), and in week 24, it showed a trend of decreasing as compared with that measured in week 12 (P>0.05), but it was still slightly higher than that measured before the experiment (P>0.05);4)before and after the experiment, the contents of cells CD3+, NK and NKT had no between group difference (P>0.05). The said findings indicated that self-controlled exercising can improve the rates of expression of cells CD3+, NK and NKT in peripheral blood during the rehabilitation period of malignant tumor patients, is conducive for a tumor patient’s body immunity to monitor and immunely kill the exertion of tumor cell functions. The authors also found that there was no difference in type of cancer between cells CD3+, NK and NKT in the peripheral blood of malignant tumor patients.% 为了探讨自控锻炼对术后恶性肿瘤患者淋巴细胞亚群的影响，选取上海市癌症康复学校40名(男17名，女23名)新学员为受试对象，平均年龄为(57.50±6.84)岁，平均癌龄为(1.50±0.77)年。病种分别为消化系统癌、乳腺癌、其他类型恶性肿瘤(肺癌、卵巢癌等)。在专门人员的指导下，患者先进行3周的自控锻炼学习，之后坚持24周的自控锻炼，平均锻炼频率每周5 d，每天锻炼持续时间2 h。于试验前、12、24周分别测试患者外周血CD3+、NK、NKT细胞含量。结果发现：(1)试验第24周CD3+淋巴细胞明显升高(P<0.01)；(2)试验第12周NK细胞明显升高(P<0.05)，第24周分别明显高于试验前(P<0.01)和试验第12周(P<0.05)；(3)试验第12周NKT明显高于试验前(P<0.05)，第24周较第12周呈下降趋势(P>0.05)，但仍略高于试验前(P>0.05)；(4)试验前、后CD3+、NK、NKT 细胞均无组间差异(P>0.05)。试验结果表明：自控锻炼可改善恶性肿瘤患者康复期CD3+、NK、NKT细胞在外周血中的表达率，有利于肿瘤患者机体免疫监视和免疫杀伤肿瘤细胞功能的发挥。同时发现恶性肿瘤患者外周血CD3+、NK、NKT细胞不存在癌种差异。
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