南京地区29家医院2010-2012年麻醉性镇痛药的应用分析

摘要

Objective To evaluate the current situation and trend of narcotic analgesics used in 29 hospitals of Nanjing from 2010 to 2012 and provide references for reasonable clinical drug utility .Methods Consumption of narcotic analgesics in 29 hospitals of Nanjing was analyzed retrospectively in terms of sales value , DDDs, DDC, etc.The DDDs, sales value and variety of narcotic anal-gesics were analyzed statistically according to the level , type and district of hospitals .Results There were a total of 13 kinds of nar-cotic analgesics in the 29 hospitals and the sales value increased yearly .During the 3 years,the DDDs of fentanyl citrate injection ,fent-anyl transdermal system and remifentanil hydrochloride were ranked in the forefront and the DDDs rank of controlled -release morphine and controlled-release oxycodone hydrochloride was stable .The sales value and DDDs in Drum Tower District were greater than other districts and increased yearly .Conclusion The application of narcotics analgesic in 29 hospitals of Nanjing was rational and complied with the relevant national regulations .%目的：评价南京地区29家医院2010-2012年麻醉性镇痛药的应用情况及发展趋势，为临床合理用药提供依据。方法采用回顾性研究方法，对南京地区29家医院2010-2012年麻醉性镇痛药的销售金额、用药频度（ DDDs）、日均费用（ DDC）等进行统计和分析，并根据医院级别、类型、所在区域统计各年度麻醉性镇痛药的DDDs、销售金额及品种数。结果南京地区29家医院共涉及13种麻醉性镇痛药，各类药品销售金额呈逐年增长趋势；枸橼酸芬太尼注射液、芬太尼透皮贴剂和注射用盐酸瑞芬太尼的DDDs在3年中稳居前列；吗啡控释片和盐酸羟考酮控释片的DDDs排序3年来相对稳定。南京市区中，以鼓楼区3年来麻醉性镇痛药的销售金额及DDDs领先于其他各区，且呈逐年增长态势。结论南京地区29家医院麻醉性镇痛药的应用基本合理，符合国家相关规定。