首页> 中文期刊> 《北方药学》 >雷贝拉唑+克拉霉素+左氧氟沙星三联疗法治疗幽门螺杆菌消化道溃疡的观察

雷贝拉唑+克拉霉素+左氧氟沙星三联疗法治疗幽门螺杆菌消化道溃疡的观察

         

摘要

目的:观察雷贝拉唑+克拉霉素+左氧氟沙星三联疗法治疗幽门螺杆菌消化道溃疡的疗效。方法:60例幽门螺杆菌阳性消化道溃疡患者随机平分为两组,两组患者都采用三联一周疗法,治疗组为雷贝拉唑+克拉霉素+左氧氟沙星治疗,对照组为奥美拉唑+阿莫西林+甲硝唑治疗。结果:经过治疗,治疗组30例96.7%的总有效率明显高于对照组70.0%的总有效率(P<0.05);治疗组90.0%的HP根除率明显高于对照组66.7%的HP根除率(P<0.05)。结论:雷贝拉唑+克拉霉素+左氧氟沙星三联疗法治疗幽门螺杆菌消化道溃疡能提高疗效,提高HP根除率,值得推广应用。%Objective:To investigate rabeprazole levofloxacin clarithromycin triple therapies for Helicobacter pylori peptic ulcer effect. Methods: 60 cases of H. pylori-positive peptic ulcer patients randomly divided into two groups, both groups have adopted one week triple therapy treatment group clarithromycin rabeprazole levofloxacin therapy, the control group was omeprazole + amoxicillin amoxicillin + metronidazole therapy. Results: After treatment, the treatment group of 30 patients was 96.7% of the total efficiency significantly different than the control group and 70.0% of the total efficiency (P<0.05); treatment group 90.0% of HP eradication rate of 66.7% was significantly higher HP eradication rate (P<0.05). Conclusion: rabeprazole levofloxacin clarithromycin triple therapies for Helicobacter pylori peptic ulcer therapy can improve, enhance HP eradication rate, should be widely applied.

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