胃肠超声造影诊断胃食管反流的可行性研究

摘要

Objective To explore the feasibility and clinical value of gastrointestinal contrast - enhanced ultra-sonography in the diagnosis of gastro - esophageal reflux(GERD). Methods 120 patients with typical symptoms of GERD were selected in our hospital from Feb. 2013 to May. 2014(experimental group). In the same period,120 healthy volunteers without typical symptoms of GERD were selected(control group). Gastrointestinal contrast - en-hanced ultrasonography was conducted in two groups. Reflux time and frequency were compared and feasibility was an-alyzed. Results 5 min reflux time in the control group[(1. 08 ± 0. 26)s]was less than that in experimental group [(4. 08 ± 0. 65)s](P < 0. 05). 5 min reflux frequencies(less than or equal to 2 times)was higher in the control group(97. 50% )than that in the experimental group(15. 83% )(χ2 = 162. 9638,P < 0. 05). Conclusion Gastroin-testinal contrast - enhanced ultrasonography can show reflux objectively and clearly. It can make a preliminary judg-ment of physiological and pathological gastroesophageal reflux without paln,damage and ray harm. Patient acceptance is high,which can be used as preferred choice in clinical screening of GRED.%目的：探讨胃肠超声造影在胃食管反流（GERD）诊断中的可行性和临床价值。方法选取2013年2月~2014年5月本院消化内科收治的具有典型 GERD 症状的患者120例作为研究对象（实验组），同期选取无典型 GERD 症状的120例健康志愿者（对照组），两组均经胃肠超声造影检查。对比分析两组在反流时间和次数上的不同，分析胃肠超声造影诊断 GERD 的可行性。结果对照组5 min 内反流时间（1.08±0.26）s 明显低于实验组的（4.08±0.65）s（P <0.05）。对照组5 min 内反流次数≤2次的占97.50%，明显高于实验组的15.83%（χ2＝162.9638，P <0.05）。结论胃肠超声造影能客观清楚地显示有无反流，对生理性和病理性胃食管反流做出初步判断，具有无痛、无损伤、无射线损害等优势，患者接受度高，可作为临床筛查GRED 的首选方式。