石墨烯修饰的电极对对氨基苯酚和对乙酰氨基酚进行同时测定

摘要

利用石墨烯修饰的玻碳电极采用微分脉冲伏安法对对氨基苯酚和对乙酰氨基酚进行同时测定.实验证明在pH=5.72的Britton-Robinson(B-R)缓冲溶液中这两种物质都具有良好的氧化峰,在修饰电极上两物质的伏安峰能够很好地分开,因此可以直接对这两种物质进行同时测定.在最佳实验条件下对氨基苯酚和对乙酰氨基酚的线性范围分别为0.1～1.8,0.2～2.2 mg·mL-1,两者的检测限分别为0.067,0.074mg·mL-1.利用本文提出的方法对血清实际样中的对氨基苯酚和对乙酰氨基酚进行测定,可得较高的回收率.%A differential pulse voltammetric method for simultaneous determination of 4-aminophen and acetaminophen with graphene modified glass carbon electrode was developed. Both of the two compounds gave well defined oxidation voltammetric peaks at modified electrode in medium of pH 5. 72 Britton-Rob-inson buffer. As a result,it is possible to simultaneously determine these two compounds. Under the optimum conditions,the linear ranges of 4-aminophen and acetaminophen were 0. 1～1. 8 and 0. 2～2. 2 mg · mL-1 ,with detection limits of 0. 067 and 0. 074 mg · mL-1 respectively. This method was successfully applied for the determination of acetaminophen and 4-aminophen in serum to obtain satisfied results.