电视胸腔镜胸膜固定术治疗恶性胸腔积液的临床疗效及影响因素

摘要

Objective:To study the clinical efficacy and influencing factors of malignant pleural effusion paitents tredted with VATS pleurodesed. Methods:All 87 paitents with VATS pleurodesed from January 2011 to January 2013. Clinical data were analysed. They were treated by adopt video - assisted thoracoscope pleurodesis. Results:Clin-ical effect was 63. 2% . Total incidence of adverse reaction was 9. 1% . Karnfsky life quality stability was 97. 7% . Pleural effusion hypertrophy and package the total incidence rate was 19. 5% . Tumor types,CEA,LDH,protein con-tent,ShaPeiLin perfusion,chest water Glu levels were video - assisted thoracoscope pleurodesis treatment of malignant pleural effusion main influenced factors(P < 0. 05). Conclusion:Video - assisted thoracoscope pleurodesis in the treatment of malignant pleural effusion is effective,and the tumor types,CEA,LDH,protein content,ShaPeiLin perfu-sion,chest water Glu levels are related factors affecting the prognosis.%目的：探讨电视胸腔镜胸膜固定术治疗恶性胸腔积液的临床效果，总结影响恶性胸腔积液的相关因素。方法：回顾性分析2011年1月至2013年1月87例恶性胸腔积液患者的临床资料。全部采用电视胸腔镜胸膜固定术治疗，观察其术后的临床效果，并分析影响中位生存时间的因素。结果：电视胸腔镜胸膜固定术治疗恶性胸腔积液的总有效率为63.2％。不良反应总发生率为9.1％。Karnfsky 生活质量稳定以上的占97.7％。胸膜肥厚和包裹积液的总发生率为19.5％。肿瘤类型、CEA、LDH、蛋白质含量、沙培林灌注、胸水 Glu 水平均是电视胸腔镜胸膜固定术治疗恶性胸腔积液的主要影响因素（P ＜0.05）。结论：电视胸腔镜胸膜固定术治疗恶性胸腔积液临床效果确切，而肿瘤类型、CEA、LDH、蛋白质含量、沙培林灌注、胸水 Glu 水平是影响预后的相关因素。