无创机械通气用于 COPD 合并呼衰的临床观察

摘要

Objective:To explore the clinical application value of noninvasive mechanical ventilation in patients with chronic obstructive pulmonary disease and respiratory failure .Methods:102 patients with chronic obstructive pulmonary disease and respiratory failure were treated with noninvasive mechanical ventilation .The results of the arterial blood gas before and after the treatment were compared each other .Results:The clinical symptoms were improved after treating with noninvasive mechanical ventilation .The analysis of arterial blood gas showed that pH , PaO2 , PaCO2 and SpO2 were significantly improved ( P<0.05) after treating.9 patients had adverse reactions in 102 patients of noninvasive mechanical ventilation , of which,4 patients had throat discomfort ,2 had abdominal distension ,2 had a sense of fear or tension and 1 had skin compression injury .The incidence of adverse reaction was 8.82%.Conclusion:The noninvasive mechanical ventilation in patients with chronic obstructive pulmonary disease and respiratory failure is effective .The early application can improve patients ’ respiratory function and oxygen deficit as well as relieve carbon dioxide retention ,may save more time for treating primary disease .Meanwhile ,the noninvasive mechanical ventilation can save patients from tracheal intubation for relieving the pain and enhancing the success rate .It is worthy of clinical popularization .%目的：观察无创机械通气用于慢性阻塞性肺疾病（ COPD ）合并呼吸衰竭患者的效果。方法：对102例COPD合并呼吸衰竭患者给予无创机械通气治疗，比较治疗前后动脉血气分析。结果：患者使用无创机械通气治疗后，临床症状明显缓解，治疗后血气分析中的pH值、PaO2、PaCO2、SpO2均较治疗前有明显改善（ P＜0.05）。102例进行无创机械通气治疗的患者中出现不良反应9例，其中4例为咽部不舒适，2例为腹胀，2例出现恐惧、紧张感，1例出现皮肤的压迫损伤，不良反应发生率为8.82％。结论：采用无创机械通气治疗COPD合并呼吸衰竭能够及早改善患者呼吸功能，改善缺氧及缓解CO2潴留，为治疗原发病赢得时间，同时可以让患者免于遭受气管插管，减少患者痛苦，提高患者救治成功率，值得临床推广。