65例老年人认知功能减退影响因素分析

摘要

目的：探讨老年人认知功能障碍的影响因素，从而有助于临床的早期诊断及治疗。方法：2011年研究开始时，中文版的简易智能量表评分（ C－MMSE）证实210例参与者无认知功能障碍。随访3年后，量表评分下降≥2分的参与者被评定为认知功能下降，比较认知功能减退及未减退人群的人口学资料、生活方式等，采用Logistic回归分析影响认知功能的因素。结果：3年后，65例（30．95％）有认知功能减退，影响认知功能的因素有年龄、高血压病、糖尿病、BMI、女性绝经年龄、文化程度。结论：高龄、高BMI、高血压病史、糖尿病史是认知功能减退的危险因素，而较迟的女性绝经年龄、高的文化程度是保护因素。%Objective:To identify the influencing factors of cognitive dysfunction in elderly people, and its early diagnosis and treatment. Methods: 210 participants without cognitive dysfunction were confirmed by Chinese Mini-Mental State Examination( C-MMSE) in 2011.Followed up 3 years, their demographic data, lifestyle, etc.were compared between people with cognitive decline and those without cognitive decline.Logistical regression was used to analyze the influential factors for cognitive function.Results:After 3 years, cognitive function declined in 65 cases(30.95%).The influencing factors of cognitive function included age, hypertension, diabetes mellitus, body mass index, age of menopause, and degree of education.Conclusion:Old age, high BMI, history of hypertension and history of diabetes mellitus are the risk factors of cognitive decline, but relatively late age of menopause and high level of education are the protective factors.