Objective To explore the effects of anxiety on cognitive function and activity of daily living in Parkinson's disease patients (PD).Methods Anxiety,cognitive function and activity of daily living in 55 cases of PD patients and 30 cases of normal control group were evaluated by beck anxiety inventory(BAI),montreal cognitive assessment(MOCA) and Barthel index scale (BI).The relationship between BAI score and MoCA score or BI score were analyzed.Results The incidence of PD combined anxiety disorder was as high as 41.8％.MoCA score of anxiety group was significantly lower than the control group and significantly negatively related to the BAI scores(P ＜ 0.05),but there was no statistical difference compared with the anxiety group(P ＞ 0.05).Visual space and executive function,memory and delayed memory score and BI score of the anxiety group were significantly lower than the anxiety group and control group (P ＜ 0.05) and significantly negatively related to the BAI scores (P ＜ 0.05).Visual space and executive function of the non-anxiety group were significantly lower than the control group,but had no significant correlation with the BAI score (P ＞ 0.05).Conclusion PD patients often have a certain degree of cognitive impairment and obvious barriers to daily living activities.Anxiety often has different extent effect on cognitive function in PD patients,especially in the visual space and executive function,memory function,and seriously affects the patient's activity of daily living,makes the life quality decreased obviously.%目的 探索帕金森病(PD)患者伴发的焦虑情绪对认知功能及日常生活活动能力的影响.方法 纳入55例PD患者及30例正常对照组,分别运用贝克焦虑量表(BAI)评估其焦虑情绪,运用蒙特利尔认知功能评定量表(MoCA)及Bathe1指数量表(BI)测评其认知功能及日常生活活动能力(ADL),分析BAI评分与MoCA、BI评分之间的相关性.结果 PD患者合并焦虑障碍的发生率高达41.8％,焦虑组MoCA总分显著低于对照组,且与BAI得分呈负相关(P＜0.05),但与非焦虑组比较,差异无统计学意义(P＞0.05);焦虑组视空间与执行功能、记忆与延迟记忆得分及BI评分显著低于非焦虑组及对照组(P＜0.05),且与BAI得分呈负相关(P＜0.05);非焦虑组视空间与执行功能、记忆与延迟记忆显著低于对照组,但与BAI得分未发现明显相关性(P＞0.05).结论 PD患者常存在一定程度的认知障碍及明显的日常生活活动能力受限,而焦虑可不同程度的影响PD患者的认知功能,尤其是视空间与执行功能、记忆功能,并严重影响患者的日常生活活动能力,使其生活质量明显下降.
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