肥胖痰湿体质多囊卵巢综合征患者临床特征分析

摘要

目的 通过比较肥胖痰湿体质与肥胖非痰湿体质多囊卵巢综合征(PCOS)患者的临床特征及生化指标,揭示肥胖痰湿体质PCOS患者的临床代谢特征,为肥胖痰湿体质的PCOS患者的治疗提供理论依据.方法 选取临床科研信息共享系统内肥胖痰湿体质与肥胖非痰湿体质的PCOS患者,提取两组患者的临床体征及生化指标.结果 两组PCOS患者在年龄、身高、体重、体重指数、腰围、臀围、腰臀比、收缩压、舒张压方面组间差异无统计学意义(P＞0.05).两组PCOS患者在FSH、LH/FSH方面,组间差异有统计学意义(P＜0.05);在LH、T、DHEAS、AND、SHBG、FAI方面,两组间比较差异无统计学意义(P＞0.05).肥胖痰湿体质的PCOS患者5点血糖、180min胰岛素水平明显高于非痰湿体质的PCOS患者.结论 痰湿体质的多囊卵巢综合征患者更易发生糖脂代谢异常,临床中应重视糖耐量试验和胰岛素释放实验,以便尽早对糖耐量受损、糖尿病等远期并发症进行防治.%Objective To reveal the metabolism characteristics of polycystic ovary syndrome in obese women of phlegm constitution through comparing the patients' clinical and biochemical characteristics.The study provide theoretical basis for the treatment of these patients in order to improve the clinical effect.Methods We selected patients and extracted the clinical and biochemical characteristics from the clinical scientific research information sharing system to compare and analyse between polycystic ovary syndrome in obese women of phlegm constitution and non-phlegm constitution.Results There were no statistic differences in ages,height,weight,BMI,WC,HC,WHR,systolic blood pressure and diastolic blood pressure during the two groups (P ＞ 0.05).Significant differences were found in FSH and LH/FSH between the two groups(P ＜0.05) and no significant differences were found in LH,T,DHEAS,AND,SHBG and FAI between the two groups(P ＞ 0.05).The levels of OGTT and 180-minute insulin of phlegm constitution patients were significantly highter than that of non-phlegm constitution patients(P ＜ 0.05).Conclusion The situation of glucose and lipid metabolism disorders was more likely to appear in the obese patients of phlegm conititution with polycystic ovary syndrome.We should better to pay attention to glucose tolerance test and insulin release test,and prevent and treat of impaired glucose tolerance and diabetes as soon as possible.