压力导丝在冠状动脉临界病变处理中的意义

摘要

Objective:To evaluate the significance of pressure wire in dealing with critical lesion during coronary artery intervension. Methods: 62 patients with critical lesions diagnosed by coronary angiography were divided into two groups: the treatment guiding of coronary fractional flow reserve (FFR group) and the treatment according to opreator experience of the past (control group). The number of stents and the cases of stem implantation were observed, and the incidence of major cardiovascular events. Within one year were also observed at the same time. Results: There was no significant differences in degree of coronary artery disease between the two groups. Total of 42 coronary artery stenosis. 8 patients underwent coronary intervention in the treatment, stenting of 12 in FFR group, and total of 56 coronary artery stenosis. 15 patients underwent coronary intervention in the treatment, stenting of 26 in control group. There was a significant difference ( P<0. 05). There was no significant difference (0% vs 0%. P >0. 05) in the incidence of MACE between the two groups after mean follow-up of 11. 2 months. Conclusion:The treatment under the guidance of the FFR is safe. The implanted stent significantly reduced under the FFR guidance, and accordingly the medical costs.%目的:评价压力导丝在冠状动脉临界病变处理中的意义.方法:62例经冠脉造影确诊为冠状动脉临界病变的患者,分为冠状动脉血流储备指导治疗组(FFR组)及根据术者以往治疗经验指导治疗组(对照组).观察两组患者支架置入例数及支架置入数量,同时观察两组患者1年内主要心血管事件发生率.结果:两组患者在冠状动脉病变程度上无明显差异,其中FFR组共有42处冠脉狭窄病变,有8例患者行冠脉介入术治疗,置入支架12枚.对照组共有56处冠脉狭窄病变,有15例患者行冠脉介入术治疗,置入支架26枚.差异有显著性(P＜0 05).术后平均随访11.2月,两组MACE发生率(0％ vs 0％,P＞0,05)无显著差异.结论:在FFR指导下决定行冠脉介入术治疗是安全的.由FFR指导植入的支架数量显著减少,医疗费用也相应显著降低.