颈动脉重度狭窄伴MCI老年患者支架植入术后认知功能变化研究

摘要

目的 了解颈动脉重度狭窄伴MCI(mild cognitive impairment,轻度认知功能障碍)老年患者,经过颈动脉支架植入术治疗后认知功能的变化.方法 应用蒙特利尔认知评估量表对32例患者在行颈动脉支架植入术前及术后1、3、6个月进行认知功能评估,并利用统计学分析对各时间点MoCA分值组间进行对比研究.结果 支架植入治疗后随访的1、3及6个月,MoCA评分较术前明显提高；而且随着随访时间延长,MoCA评分有上升趋势；MoCA分值的提高有显著的统计学意义.结论 颈动脉支架植入术可以使老年MCI伴颈内动脉起始段重度狭窄患者短期内的认知功能得到较大程度的改善.%Objective To find out the change of cognitive function in the MCI senile patients with severe internal carotid artery stenosis after carotid artery stenting. Methods Total 32 MCI senile patients with severe internal carotid artery stenosis were treated with carotid artery stenting. All the patients were examined with MoCA before treatment and 1. 3 and 6 months after treatment. We utilized statistical analysis to contrast and analyze the every time group MoCA scores. Results After treatment of 1, 3 and 6 months, the scores of MoCA were elevated significantly. The longer the follow-up time the higher the MoCA score in these group. The elevation of MoCA was statistic. Conclusion The carotid artery stenting can improve cognitive function in the MCI senile patients with severe internal carotid artery stenosis during short-term follow-up.