Cerebral Haemodynamic and Metabolic Changes in Carotid Artery Occlusion: A PET Study

摘要

Using the positron emission tomography, with the O exp 15 inhalation technique, the cerebral blood flow (CBF), the oxygen extraction fraction (OEF) and the cerebral metabolic rate of oxygen (CMRO sub 2 ) were studied in 37 patients with internal carotid artery (ICA) occlusion. In the territory of the occluded ICA, two pattern of focal anomaly have been observed: a CBF decrease with a ''compensatory'' OEF increase or a matched CBF and CMRO sub 2 decrease. On the other hand, as compared to age matched control values, CMRO sub 2 is significantly decreased in the territory of the occluded carotid only in patients with extensive neck vessels obstructive disease. (ERA citation 10:045200)