下肢深静脉血栓引起症状性非高危肺栓塞的相关危险因素分析

摘要

Objective To determine the associated factors to symptomatic non-high risk pulmonary embolism in patients with lower extremity deep venous thrombosis .Methods Clinical data in a total of 85 non-high risk PE patients caused by DVT were retrospectively analyzed .Taking occurrence of symptom or not as a dependent , and the computerized tomographic obstruction in-dex (CTOI),right-to-left ventricular diameter ratio (RV/LV), risk stratification of PE, the type of DVT, laterality of leg, age and sex as independents , multivariate binary logistic regression analysis was used to estimate the risk factors of occurrence of symptom in non-high risk PE patients .Results Logistic regression analysis showed that laterality of leg , sex and risk stratifica-tion of PE were influential factors of occurrence of symptom in non-high risk PE patients ( P =0.040, 0.017, 0.011;95%CI:1.236~8.178, 0.076~0.777, 1.626~39.898).Conclusion For non-high risk PE,the right leg DVT, female and severity of PE are risk factors to symptomatic PE .CTOI and RV/LV are not correlated with symptomatic PE .%目的：探讨下肢深静脉血栓（ DVT）引起症状性非高危肺栓塞（ PE）的相关危险因素。方法回顾性分析85例DVT引起非高危PE患者的资料，以是否出现症状作为因变量，以CT阻塞指数（ CTOI）、右左心室直径比值（ RV／LV）、PE危险分层、DVT类型、患病肢体、年龄及性别为自变量引入二元模型进行Logistic回归分析，探求引起非高危PE症状的危险因素。结果 Logistic 回归分析显示患病肢体、性别、PE危险分层是导致PE出现症状的影响因素，（ P值＝0.040、0．017、0．011；95％的可信区间：1．236～8．178、0．076～0．777、1．626～39．898）。结论对于非高危PE而言，右下肢DVT、女性及PE严重程度是PE出现症状的危险因素，CTOI及右左心室直径比值与PE是否出现症状无关。