Objective; To investigate the choice of operative opportunity and prevention of intraoperative complications in lapa-roscopic cholecystectomy (LC) for acute calculous cholecystitis. Methods: The clinical data of 127 patients who suffered from acute -calculous cholecystitis and underwent LC were retrospectively analyzed. Results:LC was successfully performed in 125 cases,2 cases were converted to laparotomy. Secondary calculus of bile duct occurred in 3 patients,who underwent endoscopic sphincterotomy 3-5 days after LC. Bile leakage was found in 1 patient,who was performed laparotomy 24 h after LC. No other complications were found. Conclusions:Once the diagnosis of acute calculous cholecystitis is definite, LC should be performed as soon as possible whatever the course of disease is,the operative procedure should be applied in 3 days. Conversion to laparotomy is necessary when LC is difficult. Surgeon strictly following LC operative principle and intraoperative careful anatomy are very important for decreasing and avoiding the LC complications.%目的:探讨急性结石性胆囊炎行腹腔镜胆囊切除术(laparoscopic cholecystectomy,LC)手术时机的选择及术中并发症的预防.方法:回顾分析2008年1月至2011年6月为127例急性结石性胆囊炎患者施行LC的临床资料.结果:125例顺利完成LC,2例中转开腹.术后继发胆管结石3例,均于术后3～5d行经内镜十二指肠乳头括约肌切开取石术.术后发生胆漏1例,于术后24h立即行开腹手术处理.余者均无并发症发生.结论:急性结石性胆囊炎一旦明确诊断,不论病程长短,应尽早施行LC,最佳手术时机为72 h内；术中操作困难及时中转开腹.有效减少或避免急性结石性胆囊炎LC手术并发症的关键是严格遵循LC操作原则；此外,术中耐心、细致地解剖是另一重要保证.
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