Objective To explore the transvaginal color Doppler ultrasound examination endometrial parameters before and after intrauterine infusion of streptomycin,to observe the curative effect of streptomycin in different causes of infertility.Methods 127 patients with infertility were randomly divided into streptomycin perfusion group (n=83) and normal saline control group (n=44),including 22 cases of endometrial tuberculosis,9 cases of recurrent abortion,18 cases of repeatedly planting failure,12 cases of endometrial polyp and 22 cases of endometritis.After intrauterine infusion of streptomycin,a comparison was made between each perfusion group before and after treatment,and the perfusion group and the control group were compared after treatment regarding pregnancy outcomes and transvaginal color Doppler ultrasound parameter changes.Results The infective endocarditis and endometrial tuberculosis group had EMI (P ＜ 0.05),a lower uterine spiral artery PI and RI values (P ＜ 0.05),and the clinical pregnancy rate was higher than the control group (P ＜ 0.05).Conclusion Streptomycin through intrauterine infusion can improve the endometrial receptivity of patients with endometritis and endometrial tuberculosis,and thus increase the clinical pregnancy rate.%目的 探讨经阴道彩色多普勒超声检查宫腔链霉素灌注治疗前后子宫内膜参数变化,观察在治疗后不同病因不孕症中的疗效.方法 不孕症患者127例,随机分为链霉素灌注观察组(83例)和生理盐水对照组(44例).观察组中子宫内膜结核22例,复发性流产9例,反复种植失败18例,子宫内膜息肉12例,子宫内膜炎22例;对照组中子宫内膜结核11例,复发性流产5例,反复种植失败8例,子宫内膜息肉7例,子宫内膜炎13例.链霉素灌注治疗后,比较观察组灌注前后经阴道彩色多普勒超声参数的变化,观察两组妊娠结局.结果 链霉素灌注治疗后,内膜炎及内膜结核患者子宫内膜—肌层交界区低回声区减少,子宫螺旋动脉搏动指数及阻力指数降低,内膜炎患者子宫内膜血流动脉分支增多,P＜0.05;内膜炎患者及内膜结核患者临床妊娠率明显高于对照组,P＜0.05.结论 经阴道彩色多普勒超声检测子宫内膜及测量子宫螺旋动脉的血流动力学参数,能较好地评估子宫内膜容受性;链霉素宫腔灌注可以改善内膜炎、内膜结核患者子宫内膜容受性,提高临床妊娠率.
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